Even if you have never touched cannabis, there are cannabinoids in your body. Your endocannabinoid system is a central regulatory system that affects a wide range of biological processes, including appetite, pain sensation, mood, sleep, and memory. In studies where mice were genetically bred to lack a proper endocannabinoid system, the most common result was premature death. Experts believe that the main overall function of this system is to regulate homeostasis. Homeostasis is a key element in the biology of all living things, best described as the ability to achieve stability or balance in a system. It is the body’s attempt to maintain the consistent internal environment it needs to survive, constantly making adjustments as conditions change. Our ability to do this tends to decline with age, and most illnesses involve a failure to achieve homeostasis; without it, there is no chance for health or wellness.
At Sespe we believe all cannabis use is medicinal in some way, whether it is done for recreation or for relief. We are connected with this plant at a molecular level, a symbiotic relationship that has lasted at least ten thousand years and possibly much longer — in fact it may have been the first cultivated crop. It featured prominently in the world’s first written pharmacopeia, and in every one since then. Every major civilization has harnessed its power, whether for healing, enlightenment, or pleasure. Cannabis has been part of the human experience since the stone age; the prohibition of the past hundred years or so was an aberration, not the norm.
Whether you’re here for the medicine or for the blissful side effects, welcome. Our guide for new consumers is split up in four parts: