Even if you have never touched cannabis, there are cannabinoids in your body. Your endocannabinoid system is a central regulatory system that affects a wide range of biological processes, including appetite, pain sensation, mood, sleep, and memory. In studies of mice genetically bred to lack a proper endocannabinoid system the most common result is premature death. Experts believe that the main overall function of this system is to regulate homeostasis. Homeostasis is a key element in the biology of all living things and is best described as the ability to maintain stable internal conditions that are necessary for survival. Most of the clinical conditions patients present are a result of a failure to achieve homeostasis, making the endocannabinoid system a unique target for medical applications. Thus cannabis has the potential to treat not only the symptoms of disease, but the disease itself.
Sespe's guide for new patients is split up in four parts: